When knowledge meets collaboration, real innovations happen. One recent example comes from research into the role of dietary fibres in gut health. At the request of TNO, we shared this initiative within our communities and connected them with relevant partners. This resulted in a collaboration of 6 parties, including Foodvalley partners FiberFoodsGroup (jackfruit), Saledo (green banana flour) and BioAG (humic acid), alongside three other partners (PectCof, MyMicroZoo and Perseus Biomics). Together, they have explored how dietary fibres influence the human gut microbiome.

The health benefits of dietary fibres are widely recognised, particularly in preventing certain diseases, yet the mechanisms behind these effects are still not fully understood. Using TNO’s i-screen platform, the team fermented the products in the laboratory with gut microbiomes from healthy individuals. They found that several products stimulated the production of short chain fatty acids such as acetate, propionate and butyrate. These compounds are linked to a variety of processes in the body and higher levels are generally seen as beneficial.

The research also showed a strong increase in specific bacteria, including Faecalibacterium prausnitzii and Eubacterium eligens, both known for their role in producing short chain fatty acids. Consuming these fibres may enhance the composition and function of the gut microbiota, potentially leading to improved gastrointestinal health in consumers. Demonstrating these benefits could drive product sales and open up novel market niches. In particular, gastrointestinal health is currently a prominent topic of interest—not only among consumers but also within the food industry. The promising results have already led to discussions on follow-up projects, including new studies on the effects of proteins on the gut microbiome.

For TNO, this collaboration was valuable not only for gaining deeper insights into dietary fibres and their role in stimulating specific bacteria, but also for initiating partnerships with startups and SME companies. This collaboration highlights how the right connections and co-creation can accelerate innovation and lead to discoveries with real impact on health and well-being. By working together, we can drive scientific discovery and shape healthier futures.